the nation's most populous city has a reputation for hosting a bustling population of unwanted pests, the "rattiest" city in the United States is not New York City, whose mayor has publicly waged war on the rodents. That spot belongs to Chicago, according to pest control company Orkin. The national chain ranked the top 50 most mice-and-rat-infested metropolitan regions nationwide based on the number of residential and commercial rodent removal jobs the company performed from Sept. 2021 to Aug. 2022. Click the link in our bio to learn more about the “rattiest” cities in the U.S.